Slow growth, reduced egg production, reduced size and reduced hatchability of eggs. Fat accumulation in liver and kidney, hepatic steatosis, detendinopathy, behavioral disorders, muscular dystrophy.

Slow growth, behavioral disturbances, neurological disorders, muscular dystrophy, poor fertility, excess fat storage in the liver.

Breathing disturbances, behavioral disturbances, loss of appetite, slowed growth.

Slow growth, fatty liver, poor feeding efficiency, renal and intestinal bleeding.

It is derived from the reaction between trimethylamine and ethylene oxide.
The trimethylamine ethanol solution was added to the reaction pot, and ethylene oxide was introduced into it at about 30°C, and the reaction was stirred for 4 hours, and then neutralized with hydrochloric acid (controlling pH 6.5-7.0). The crude product yield can reach 98%. After decolorization with activated carbon and vacuum concentration, a 70% aqueous solution can be obtained. Add corncob flour, rice husk flour, bran or diatomaceous earth and other excipients to the aqueous solution to obtain 50% powder.

Substitute ethylene oxide and hydrochloric acid with chloroethanol, and react with trimethylamine under the catalysis of a small amount of ethylene oxide or an alkaline substance: first add 100 parts of chloroethanol to the reaction kettle, add 130 parts of trimethylamine from the liquid surface, Simultaneously, 1.7 parts of ethylene oxide was introduced to initiate the reaction. After adding, it was kept at 32-38°C and stirred for 4h, the yield was 84% (calculated in chloroethanol). If catalyzed by alkaline substances (such as quaternary ammonium salts), the single-pass conversion rate can reach more than 97%.